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There's a release of norepinephrine through the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors within the dorsal horn to minimize afferent discomfort transmission and develop analgesia. Therefore, medication like clonidine that target alpha-two receptors can affect the transmission of pain. Clonidine is a long-phrase medication. It comes along https://richardy950rhw5.wikifrontier.com/user

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