There's a release of norepinephrine through the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors within the dorsal horn to minimize afferent discomfort transmission and develop analgesia. Therefore, medication like clonidine that target alpha-two receptors can affect the transmission of pain. Clonidine is a long-phrase medication. It comes along https://richardy950rhw5.wikifrontier.com/user