Limb-threatening or essential limb ischemia (CLI) is manifested by Long-term (in excess of two months) ischemic relaxation agony, ischemic wounds or tissue loss, or gangrene in one or equally legs. Ischemic relaxation soreness typically takes place quickly soon after falling asleep; the individual is awakened by burning pain or numbness https://www.sgvascularctr.com/treatment-of-peripheral-artery-disease-pad-in-singapore-a-comprehensive-guide/