Tramadol and its metabolite, O-desmethyltramadol (M1), are existing in human milk. There is absolutely no information on the results with the drug within the breastfed infant or the results on the drug on milk output. The M1 metabolite is much more powerful than tramadol in mu opioid receptor binding [see https://deanzvpfp.bloggosite.com/44691368/about-sleeping-tablets-zopiclone-7-5mg